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Effects Of Cancer On Mental Health

Even today after so much advancement in the field of healthcare and medicine and so much rewarding research around cancer, it still remains a dreaded disease for people. Yes, innovation and research in the cancer field has brought about a lot of hope in terms of increasing longevity and improvement in quality of life, even today when we hear of been diagnosed with cancer, we do get goose bumps or a shocker. These days’ people have become quite vocal about disclosing the diagnosis to people and sharing their experiences particularly celebrities are quite vocal about it. Even though, different people experience differently depending upon their individual mental health.

Most of us feel that having cancer means a physical condition that is life threatening, causes fatigue, hair loss and nausea. But, beyond physical issues, comes the mental health issue which we are not able to see. Some might tell about it while some may not but the fact of the matter remains that hearing the news does not get easier for anyone. There comes some point in life where most of the cancer patients slip in depression. Here are the most common feelings that storm through the minds of cancer survivors –

cancer Hospital in Bangalore

DEPRESSION – As per the National Cancer Institute, depression is known to affect around 15 to 25 percent of the cancer population. The condition is a result of diagnosis itself primarily. Other reasons for depression include cancer side effects, anxiety around the future with cancer, change in image of self, to name a few. Depression is not the same as feeling sad, it comes with symptoms like fatigue, emptiness, mood swings, worthlessness to name a few.

vims bangalore

GRIEF – Grief is not limited to the cancer patient but to his family and relatives as well for the period through the cancer battle. There is this term called anticipatory grief, apparently a mix of emotions that come when we live with a personal loss experience that results into grieving. This same grief is experienced by cancer patients and their relatives. Although it is normal to experience grief in such times, but grieving alone isn’t advisable.

ANXIETY – Anxiety is one of the most common problems that cancer patients face around their future prognosis, future reports, treatment related issues to name a few. The cancer community has also coined a special work for anxiety around future scans, calling it scanxiety.

All these mental health issues do need to be looked into and consulting a mental health specialist or therapist surely does help. Well, it important to understand that if mental health is better, the healing is faster and even the quality of life.

Vydehi is one of the best cancer hospital in banglaore, recently vims started VOICE – Vydehi Oncology Institute and Center of Excellence

*Sourced from the Internet

Risk of Breast Cancer in Trans Women Post Hormone Therapy Escalates To Over 45 Times

A Study has found that trans-women undergoing the gender change procedures increase their risk of getting breast cancer by over 46% as compared to men. The study was carried out on over 2000 trans-women and it was found that after undergoing the sex change procedures 1 in 200 came under the risk scanner of breast cancer as compared to less than 8000 in men.

Cancer hospital in Bangalore

The studies that were carried out earlier have shown that hormone replacement therapy (HRT) does increase the risk of breast cancer particularly in women post menopause. Suggestively, it would increase the risk in trans-women undergoing hormone treatment.

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As study involving 2260 women, 15 cases of invasive breast cancer came to light of that of women of over 50 years of age post 18 years on an average of hormone therapy. Dr. Martin Den Heijer from Amsterdam University Medical Centre says that the issues and side effects of hormone therapy are knowns are discussed also with the people who undergo treatment.

Though the risk for naturally born women is one third less, the experts from Netherlands said that not only the patients but even the doctors needed to be aware of the fact that injections of female hormones do have an increased threat.

vydehi medical institutes in bangalore

In Britain there has been a drastic rise in the number of operations and it’s around 250 per year presently as compared to 54 around 2000. The researchers were unclear though if some of the cases were genetic or due do lifestyle because one of their trans gender woman study did carry the BRCA gene mutation that lead to breast cancer. Besides, it also showed that trans- gender men were at a considerably lower risk as compared to female population. The study that determined the same involved 1229 trans men of which four had invasive breast cancer have diagnosed at 47 years post 15 years of hormone treatment.

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*Sourced from the Internet.

Cancer Vaccine that can Cure 97% of Tumor from Mice Approved for Human Trial

Yes, you read that right. As per researchers of Stanford University, a vaccine they tested on mice has worked well in curing around 97% of the tumors in mice and is ready for human trial. According to SFGate. the human trial is scheduled to be conducted on 35 people suffering from lymphoma before the year ends.

The study was earlier tested on mice with cancers ranging from colon, breast and lymphoma. The results were welcoming, because this treatment cured around 87 mice out of the 90. The best part is that tumors in some mice had spread through other parts of the body too and even then they could be cured.

Cancer Vaccine That can Cure 97% of Tumor from Mice Approved for Human trial

As per the regional director of breast surgery at North-well Health Cancer Institute in Westchester, New York, even if the news was exciting enough, the results on animals might not be the same as that on humans. So, there is still a long way to go before the treatment works for particularly cancers other than lymphoma, viz. breast and colon.

Though it is called a vaccine, technically it ain’t. It is more of an immunotherapy. It is still given the name of a vaccine for a reason that is does contain a vaccine like injection. Also, as per the American society of clinical oncology, cancer vaccines can be used for referring treatment of cancer and preventing it from coming back. This vaccine involves the injection of the vaccine into the existing tumor. It does the role of reactivating the T cells. These T cells are responsible for infiltrating and attacking the cancer cells. But, as the tumor increases, the cancer tells suppress these T cells.
Immunotherapy is not something new though. It has been in practice for quite some time. A treatment called CAR t-cell therapy has been already approved some time back for leukemia as well as lymphoma. This therapy is about removing certain immune cells from the body and genetically engineer these cells so that they become capable of fighting cancer.

But, the advantage of this therapy over CAR T-cell therapy is that nothing from the body is to be removed or customized. Here it’s just targeted therapy where the doctors will be concentrating and attacking specific targets.

Though this study is one step forward in the direction to treat cancer but still it’s a long way to go.

Vydehi Institute of Oncology & Research Centre is one of the first centers in India to commission IGRT (Image guided radiation therapy) with respiratory gating apart from having other radiation equipment like High Dose Rate Brachytherapy (HDR).

*Source from the Internet

One Blood Test to Diagnose 8 Different Cancers

A recent study has revealed the ability of one blood test to detect as many as eight types of cancers with perfection. The study was carried out by a team of researchers at the John Hopkins University of Medicine, Baltimore and even published in the Science Journal. The study was carried out over 1000 people with the disease and showed high specificity and sensitivity as well.

Today, even with many innovations and advances in science, Cancer is still not having a cure. While research is on, the estimated death toll by 2030 across the world due to cancer can go up to a staggering 8-13 million range.

One Blood Test to Diagnose 8 Different Cancers

Because, cure is still to be found, the effectiveness of the treatment is limited to restricting the spread of the cancer cells and increasing life span. An early diagnosis is always beneficial in cancer but sadly, by the time you become aware of the cancer in your body, it is too late and its spread to other parts. The reason is lack of advanced tools for diagnosis. But, here’s some good news from the research team at John Hopkins University could crack the code to simple way to detect cancer that too in the early stages.

The idea is to detect small fragments of mutated DNA as well as proteins that the cancerous tumors release in the blood stream, when they are formed, thus helping to detect cancer through a blood test. The researchers revealed that the new blood test has the ability to identify 16 gene mutations as well as 8 proteins linked to eight different cancer types.

The cancers include colorectal cancer, lung cancer, breast cancer and five others that even today do not have routine screening tests for people with average risk namely pancreatic cancer, liver cancer, esophageal cancer, stomach cancer and ovarian cancer.

As per the Cristian Tomasetti, associate professor of oncology and biostatistics of John Hopkins University, the uniqueness of this classification method in observing different levels of Proteins together with DNA mutations in order to reach to a final decision.

The Cancer SEEK test was performed on 1005 individuals in total and successfully identified 70% of the cancers with high sensitivity ranging from 33% in breast cancer cases and upto 98% in ovarian cancer cases. In the five cancers which do not have routine screenings, the test performed even better showing a sensitivity of 69% to 98%.

As far as specificity is concerned the range was 99% and out of the 812 people tested, it only showed seven false results. What’s more the test was even able to detect the location of the tumor in over 80% of the patients.

As per the researchers, it will take further study to determine its efficacy as a routine screening test for cancer detection but the results are encouraging and definitely paves the way towards improving quality of life of cancer patients through early detection.

VIMS is one of the best cancer hospital in India, with 300 beds exclusively for cancer patients.Oncology department in the hospital has got qualified and well experienced doctors

Oral Cancer – Types – Risk Factors – Symptoms – Diagnosis – Stages – Treatment

The cancer that develops in the tissue of mouth or throat is known as oral cancer and belongs to head and neck cancer group. The cancer usually occurs in people over the age group of 40 and there are thousands of people suffering from oral cancer every year. The survival and treatment is based on the diagnosis and the stage of detection.

Oral Cancer types
1. Tongue Cancer
2. Lips Cancer
3. Gums Cancer
4. The floor of the mouth
5. The inner lining of the cheek
6. Hard and Soft palate

Risk Factors
Oral cancer is most common in people chewing tobacco in different forms like pipes, a cigar as well as in people who consume alcohol. Male are twice at risk of oral cancer compared to women. Besides, the following risk factors can cause cancers as well.
• The family history of oral or any other cancer
• Poor Nutrition
• Weak immune system
• Human papillomavirus (HPV) infection
• Chronic facial sun exposure

Oral Cancer

Symptoms
• A lump growth anywhere inside the mouth
• Bleeding from the mouth
• Trouble swallowing or wearing dentures
• Loose teeth
• A lip or mouth sore that does not heal
• A sore throat
• Red or white patches on lips or inside the mouth
• Jaw or tongue pain or stiffness

Diagnosis
The diagnosis can be done using either X-ray, CT Scan or an MRI scan. MRI’s can show highly accurate results on cancer of neck and head with the stage of it while PET scan can be done in order to check whether the cancer is reached to the other organs or lymph nodes. X-ray can help determine whether cancer has spread to chest, lungs or jaw. CT scan is also used to diagnose cancers in organs like lungs, neck, mouth, and throat.

Stages
There are four stages through which cancer progresses and the survival rate also varies based on the stage of detection of the cancer
Stage 1 – The tumor at this stage is around 2 cm or even smaller and the cancer is not yet spread to the lymph nodes. Survival rate at this stage is quite high
Stage 2 – The tumor is over 2 cm but under 4 cm in size and cancer hasn’t spread to the nodes. The survival rate is good if the cancer is detected at this stage
Stage 3 – This is a bit advanced stage where the tumor is over 4 cm and it hasn’t spread to the lymph node or is of any size and has spread to one of the lymph nodes. The survival rate is reduced at this stage
Stage 4 – This is the final stage and cancer has a tumor of any size that has spread to other lymph nodes as well as other parts of the body.

The survival rate for over 60% of people with oral cancer is said to be up to five years or more. The earlier the diagnosis happens, the more is the rate of survival and hence it is the most for localized cancer (83%), 64% for cancer that has spread to lymph nodes and 38% for last stage cancer.

Treatment
The treatment of oral cancer depends on the diagnosis and the type, location, and stage of cancer.
The treatment includes –
Surgery – The initial treatment involves removal of the cancerous tumor and lymph nodes. If required some other tissues might be removed from the neck and mouth.
Chemotherapy – This therapy involves removal of the cancerous cells using drugs. The therapy is carried out on an outpatient basis, wherein the medicine is provided orally or via (IV).
Radiation Therapy – The therapy is a process of two to eight weeks wherein the doctor projects radiation beams at the tumor once or twice a day. For advanced stage cancers, a mix of chemotherapy and radiation therapy is carried out.
Targeted Therapy – Targeted therapy is another form of therapy which works well will containing the growth of cancer cells. The drug binds with specific proteins on cancer cells in order to interfere with their growth.

Cancer treatment can take a toll on your diet making it difficult to eat and swallow. Hence, it is important that you discuss your nutrition with the doctor which provides you with all the need nutrients and is even painless for you to an extent.

Vydehi is one of the best cancer hospital in Bangalore, recently vims started VOICE – Vydehi Oncology Institute and Center of Excellence.

Prostate Cancer – An Overview

This cancer occurs in the male reproductive system to the prostate which is a gland that is just outside the bladder around the male urethra. This is one of the most common forms of cancer that occurs in men usually above 50 years of age. The people who have fathers or brothers diagnosed with prostate cancer at a younger age are at more risk of getting this cancer.

Here is a run down through the symptoms diagnosis treatment and survival span for patients suffering with prostate cancer. Prostate cancer consists of adenocarcinoma cells that originate from the glandular tissue. So, even if the cancer spreads through the bones, it is not called bone cancer but is known as prostate cancer metastatic to bones. Commonly prostate cancer metastasizes to the lymph nodes located in the pelvis and also to the bones.

prostate cancer

Risk Factors
As for the cause of prostate cancer, it is yet to be known though genetic factors are known to be responsible for the same. Though research is still on to figure out the exact cause of the condition.

Symptoms
Prostate cancer patients exhibit the following symptoms which mainly include urinary issues
1. Hesitancy or difficulty in starting
2. Nee to put stain for urinating
3. Decrease in force of urine
4. Intermittency or irregular flow of urine
5. Frequent bathroom visits
6. Dribble
7. Burning or pain during urinating
8. Erectile dysfunction
9. Painful ejaculation
10. Blood or semen in urine
11. Lower back or pelvic or abdominal pain
12. Unexplained weight loss, swelling in lower extremities and bone pain

Diagnosis
Prostate cancer screening needs to be done at regular intervals particularly after 40 or 45 if you have it in the genes. The testing involves prostate specific antigen (PSA) test and digital rectal examination. Though it has its own pros and cons hence it important to consult an urologist before doing such screenings.
If the PSA is abnormally high, or there is an abnormal area felt during rectal examination, the risk is raised.
Prostate biopsy can help confirm the possibility of having prostate cancer

Treatment
The treatment procedure involves observation of the cancer, monitoring it continuously, surgery also known as radical prostatectomy, radiation therapy, chemotherapy, hormone therapy as well as other therapies in order to limit the growth of cancer cells.

There are a lot of cancer deaths in the world but if timely diagnosis is carried out you can increase the survival rate and avoid deaths that are caused due to detection at the last stages.

Vydehi is one of the best cancer hospital in bangalore, recently vims started VOICE – Vydehi Oncology Institute and Center of Excellence.

Cancer Can Now Eliminate Tumors In Mice

A recent study by Stanford researchers have states that on activating T cells in Tumor, you can eliminate even distant metastases in mice. The researchers carried out the research in mice by injecting minimal quantity of two immune stimulating agents into solid tumors present inside mice. The researchers added that the idea could work well even on distant metastases and a variety of cancers as well.

Cancer Can Now Eliminate Tumors In Mice

The researchers further added that this therapy could turnout to be inexpensive comparatively and almost without any adverse side effects. The best part of this new finding is that the use of two agents together helps eliminate all the tumors in the body without a targeted approach to immune specific targets or wholesale activation of the immune system.

The development of the first of a kind monoclonal antibody, known as rituximab has been approved for cancer treatment in human beings. This approach makes use of small quantity of two agents in order to stimulate the immune cells within the tumor itself. The one time application of the same has displayed amazing results by eliminating all tumors in the studied animal. The method apparently reactivates the cancer specific T cells after the agents are injected in microgram amount into the tumor. Some tumor specific T cells also leave the place where they are injected, find other similar tumors in the body and eliminate them. The results have been awe-inspiring because out of the 90 mice 87 have been cured completely.

Now, the clinical trial involving humans is to begin. Initially 15 patients with low grade cancers are going to be experimented upon and if the results are as desired then the clinicians are aiming to inject the two mentioned agents in solid tumors before the surgical removal of them in order to prevent relapse of the same. As per the researchers, there is no limit on the type of cancer that could be treated using this technique as long as it can be infiltrated by the immune system.

The expected results of the test might as well pave the path to inexpensive cancer treatment therapy with astounding results.

*source from internet

A Technique To Destroy Cancer Cells Within Three Days

A new study has further raised the hope for treating cancer faster due to the easy technique which alters the structure of chromatin in cancer cells thus destroying them faster and in an easier way.

Now chromatin is formed from DNA that are wrapped around proteins and called Histones. Chromatin is responsible for regulating the genes that are switched on and off besides packaging the genetic code into the cell nucleus properly. In technical language you may put chromatin as the software if the genetics is termed as hardware.

A Technique To Destroy Cancer Cells Within Three Days

Though chromatin works for cancer cells in a way because it aids in their evolution and helps them adapt to cancer therapies, ultimately helping them survive and grow.
Cancer being a complex condition, individual behavior of genes does not make a difference but it all actually depends on the complex interplay of the thousands of genes. Hence, the researchers focused on chromatin for fighting cancer.

They developed the technique called Partial Wave Spectroscopic (PWS) microscopy, which allows real time monitoring of chromatin in living cells. They used this technique in cultured cancer cell and found that chromatin helps cancer cells evade treatment due to the specific packaging density linked with gene expression.

The more disordered and heterogenous the chromatin packaging density, the more ordered and conservative it is, the more are the chances of cancer cell death while responding to chemotherapy. Thus as per the discovery made, the researchers came to hypothesis that changing the chromatin structure and making it orderly can actually help in increasing cancer cells treatment vulnerability. Further study made them understand the fact that it was possible to modify the chromatin structure in the nucleus of the cancer cells by electrolytes.

The researchers tried combining two drugs one Celecoxib used for pain relief and Digoxin used for treating fibrillation as well as heart failure. Referring this combination as chromatin protection therapeutics (CPTs), they tested it on cancer cells in the lab with chemotherapy and the results according to the researchers were remarkable.

The researchers have also successfully replicated the finding in seven different cancer kinds which is a ray of hope in the cancer treatment.

Vydehi is one of the best cancer hospital in banglaore, recently vims started VOICE – Vydehi Oncology Institute and Center of Excellence

*Source form internet

Zika Virus and Brain Cancer

One of the most dreaded diseases in India is Cancer and its various varieties. As on day there are a variety of treatments available to treat cancer through surgeries and therapies. But, we are yet to find a treatment that guarantees uprooting cancer from its root and even vaccines to avoid it altogether. Here’s some update on zika virus and its association with brain cancer.

Zika Virus and Brain Cancer

Most of us are aware of the havoc that Zika virus has been creating since its outbreak in the south african countries. But, we are less known of some new updates on the same. Researchers apparently have found out its usage in brain cancer treatment beyond its significant threat to the unborn children.

Though untested in humans yet, the results after testing on lab dishes and animals do reveal that could help treat brain cancer. Its already known that in infants and fetus, the zika targets the brain stem cells which are found in abundance in their brain cells and kills them. This usually increases the chances of neurological issues in new borns infected with zika. But, zika is not able to target adult brains with the same effectiveness. Comparatively, the effect is less severe plus these viruses have the ability to target and kill the lethal glioblastomas, stem cells which are lethal and are not affected by chemotherapy or radiation therapy and trigger the cancer again post treatment.

This research had further created rays of hope in treating brain cancer but requires further studies and tests to be carried out on animals before trying out on humankind. The reason mainly revolves around safety issues related to zika virus. Presently, there are research groups that are also testing other virus like polio, herpes and more in order to target glioblastomas. The use of zika virus as a brain cancer healer aide might require quite some time and a lot of further testing before it hits the cancer hospitals across the world.

All You Need To Know About throat Cancer

Though we as humankind haven’t had a breakthrough in completely treating every kind of cancer or a vaccine in protecting ourselves from it, if we are alert enough, there is every possibility of catching hold of it at an early stage so as to treat it well before it goes out of control. One such cancer type is throat cancer. As goes its name, it is the cancer of throat and affects the pharynx as well as the larynx or voice box. While the pharynx is located above the esophagus and larynx and below the nasal cavity, the larynx is located in the front of the neck.

Throat-Cancer-causes-symptoms

The risk factors associated with throat cancer include –
Sexually transmitted virus known as human papillomavirus (HPV)
Addictions like tobacco, gutkha, alchohol and smoking
A diet free from fruits and vegetables
Gastroesophageal reflux disease (GERD)
Genetics viz inherited defects in certain genes
Aesbestos exposure
Dental hygiene issues
Throat Cancer Stages

There are three different stages in throat cancer. If detected at an early stage throat cancer is pretty much treatable with surgery and radiation.

Symptoms of Throat Cancer
Symptoms of throat cancer include blood coughing, swelling in lymph nodes, trouble swallowing and more. Other than that some of the potential symptoms of cancer include the following
Cough that rarely goes away
Constant Throat Clearance
Unexplained Weight loss
Soar Throat
Ear pain
Hoarseness

Stages of Throat Cancer
The levels of throat cancer are spread across four stages 0 to 3.
Stage 0 – This is the earliest stage of caner wherein the tissue isn’t affected any other areas except your throat.
Stage 1 – The cancer has not affected any other areas beyond the throat but the size of it is less than or equal to 7 cm.
Stage 2 – The size of the throat has crossed 7 cm but still hasn’t invaded other organs
Stage 3 – The cancer has spread upto nearby organs and tissues.
Stage 4 – The cancer has spread to distant organs as well as lymph nodes

Throat Cancer Diagnosis
For diagnosis the doctor or oncologist may ask to do a biopsy or a fine needle aspiration. The biopsy recommended could be either a conventional biopsy or an endoscopic biopsy. The doctors would further recommend a few tests for determining the stage of your cancer. These include CT scan, PET scan or a MRI test.

Treatment of Throat Cancer
The treatment would be typically based on the stage of the cancer. It could include removal of the tumor and radiation and chemotherapy later on. It is a prolonged process and not a matter of few days. Repeated tests would have to be carried out to determine how successful the surgery, the radiation or chemotherapy therapy have been. Based on the reports the trajectory of the further treatment would be derived.

Recovery Issues
Throat cancer complications after the surgery and treatment could include disfigurement of neck and face primarily. This though can be fixed to a certain extent through surgery. The other issues that a patient may face during recovery includes breathing and swallowing difficulty, trouble while speaking and skin hardening around the neck.

Cancer of any kind is a condition which if caught hold of early on can be treated and many a times completely eradicated but this requires you to be alert and keep a eye on your health like a hawk. Regular health checkups are advisable for the same.

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